TST: A TST is an injection of a small amount of testing fluid (a derivative of the tuberculin purified protein) directly under the skin to produce a small bump at a clinic. You must return to the clinic 48-72 hours later so that a healthcare professional can inspect the area for any hardness or swelling. If you arrive outside of the window for any reason, the test must be repeated.
2-step TST: the 2-step TST is essentially the TST, done twice. Although Hawaii’s TB Branch is an advocate of “3 visit” protocol, most entities requesting a method requiring four visits to a clinic. Minimally, it will take a patient 10-12 days to complete, with either 3 or 4 carefully timed visits to a clinic.
Interferon Gamma Release Assay (IGRA): IGRA, or Interferon Gamma Release Assay, is a blood test to detect a tuberculosis infection in the body. Per the Hawaii State DOH Tuberculosis Control Program, the Interferon Gamma Release Assay (IGRA) blood test is an acceptable alternative to a TST or a 2 step. It will require one virtual visit with TB2U, and one walk-in visit to any Clinical Labs of Hawaii for a lab draw. At TB2U, we order the QuantiFERON-TB Gold plus, one of the two commercially available IGRA tests.